Sono-activable and biocatalytic 3D-printed scaffolds for intelligently sequential therapies in osteosarcoma eradication and defect regeneration

Abstract To mitigate the necessity for multiple invasive procedures in treating malignant osteosarcoma, an innovative therapeutic approach is imperative to achieve controllable tumor-killing effects and subsequent bone repair. Here, we propose the de novo design of sono-activable and biocatalytic na...

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Bibliographic Details
Main Authors: Xiao Rong, Sutong Xiao, Wei Geng, Bihui Zhu, Ping Mou, Zichuan Ding, Boqing Zhang, Yujiang Fan, Li Qiu, Chong Cheng
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61377-x
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