Tau-network mapping of domain-specific cognitive impairment in Alzheimer’s disease

Tau-network mapping of domain-specific cognitive impairment in Alzheimer’s disease

Fibrillar tau gradually progresses in the brain during the course of Alzheimer’s disease (AD). However, the contribution of tau accumulation in a given brain region to decline in different cognitive domains and thus phenotypic heterogeneity in AD remains unclear. Here, we leveraged the functional co...

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Bibliographic Details
Main Authors: Ying Luan, Anna Rubinski, Davina Biel, Diana Otero Svaldi, Ixavier Alonzo Higgins, Sergey Shcherbinin, Michael Pontecorvo, Nicolai Franzmeier, Michael Ewers
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:NeuroImage: Clinical
Subjects:
tau-PET
Functional connectivity
Symptom-lesion mapping
Alzheimer’s disease
Cognitive domain
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158224001402
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