Analyzing the impact of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) on the reproductive system using network toxicology and molecular docking

Analyzing the impact of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) on the reproductive system using network toxicology and molecular docking

Growing evidence suggests that perfluorinated compounds (PFCs) contribute to reproductive toxicity, with perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) being the most extensively studied. These chemicals are known to lower testosterone levels and compromise the integrity of the b...

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Bibliographic Details
Main Authors: Liang Chen, Shanshan Liang, Jiaxin Li, Qian Li, Qingwen Sun
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:Heliyon
Subjects:
Perfluorooctanoic acid
Perfluorooctane sulfonate
Network pharmacology
Molecular docking
Reproductive toxicity
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024154503
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