LDHA exacerbates myocardial ischemia-reperfusion injury through inducing NLRP3 lactylation
Abstract Myocardial ischemia-reperfusion (I/R) injury caused by revascularization treatment is the leading cause of cardiac damage aggravation in ischemic heart disease. Increasing evidence has unraveled the crucial role of pyroptosis in myocardial I/R injury. Of note, lactylation has been validated...
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Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-11-01
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Series: | BMC Cardiovascular Disorders |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12872-024-04251-w |
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