Reduced irradiation exposure areas enhanced anti-tumor effect by inducing DNA damage and preserving lymphocytes

Reduced irradiation exposure areas enhanced anti-tumor effect by inducing DNA damage and preserving lymphocytes

Abstract Background Partial stereotactic body radiation therapy (SBRT) targeting hypoxic regions of large tumors (SBRT-PATHY) has been shown to enhance the efficacy of tumor radiotherapy by harnessing the radiation-induced immune response. This approach suggests that reducing the irradiation target...

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Bibliographic Details
Main Authors: Huiqin Chen, Yuan Li, Qiaofeng Shen, Guanqun Guo, Zhigang Wang, Hanyu Pan, Min Wu, Xueqing Yan, Gen Yang
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Molecular Medicine
Subjects:
Radiotherapy
Target areas
DNA damage
Immune activation
Online Access:https://doi.org/10.1186/s10020-024-01037-w
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