Sex-specific DNA methylation signatures of autism spectrum disorder from whole genome bisulfite sequencing of newborn blood

Sex-specific DNA methylation signatures of autism spectrum disorder from whole genome bisulfite sequencing of newborn blood

Abstract Background Autism spectrum disorder (ASD) is a group of neurodevelopmental conditions currently diagnosed through behavioral assessments in childhood, though neuropathological changes begin in utero. ASD is more commonly diagnosed in males, a disparity attributed to both biological sex diff...

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Main Authors: Julia S. Mouat, Nickilou Y. Krigbaum, Sophia Hakam, Emily Thrall, George E. Kuodza, Julia Mellis, Dag H. Yasui, Piera M. Cirillo, Yunin J. Ludena, Rebecca J. Schmidt, Michele A. La Merrill, Irva Hertz-Picciotto, Barbara A. Cohn, Janine M. LaSalle
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Biology of Sex Differences
Subjects:
Autism spectrum disorder
DNA methylation
Whole genome bisulfite sequencing
Newborn blood
Newborn dried blood spots
Sex differences
Online Access:https://doi.org/10.1186/s13293-025-00712-9
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https://doi.org/10.1186/s13293-025-00712-9

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