Retinal revelations: Seeing beyond the eye with artificial intelligence

Artificial intelligence (AI) has revolutionized ophthalmology by aiding in the diagnosis, prognosis, and treatment planning of various eye diseases. However, AI’s potential extends beyond ocular conditions. By analyzing eye-related biomarkers, AI can utilize the eye as a window into the body’s syste...

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Main Author: John Davis Akkara
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:Kerala Journal of Ophthalmology
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Online Access:https://journals.lww.com/10.4103/kjo.kjo_124_24
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author John Davis Akkara
author_facet John Davis Akkara
author_sort John Davis Akkara
collection DOAJ
description Artificial intelligence (AI) has revolutionized ophthalmology by aiding in the diagnosis, prognosis, and treatment planning of various eye diseases. However, AI’s potential extends beyond ocular conditions. By analyzing eye-related biomarkers, AI can utilize the eye as a window into the body’s systemic health. This field, known as oculomics, leverages AI and deep learning algorithms to process vast amounts of data from imaging techniques such as fundus photography, optical coherence tomography (OCT), OCT angiography, infrared iris imaging, slit-lamp photography, and external eye photography. AI-powered analysis of these images can predict systemic diseases such as Alzheimer’s, Parkinson’s, cardiovascular disease, cerebrovascular disease, chronic kidney disease, and liver disease. Retinal changes —including alterations in the retinal nerve fiber layer, ganglion cell layer, and retinal vessels —serve as valuable indicators of these conditions. Additionally, AI can estimate age, sex, body composition, and other health parameters from eye images. While the potential of AI in oculomics is promising, challenges such as access to ophthalmic imaging, data quality, and the need for rigorous validation must be addressed to ensure its widespread adoption and clinical utility. Nevertheless, AI holds the potential to transform healthcare by enabling early detection, noninvasive screening, and personalized treatment for a wide range of systemic diseases.
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spelling doaj-art-c71df14c39c143f2b914b980127128b82025-01-07T07:34:36ZengWolters Kluwer Medknow PublicationsKerala Journal of Ophthalmology0976-66772024-12-0136329529810.4103/kjo.kjo_124_24Retinal revelations: Seeing beyond the eye with artificial intelligenceJohn Davis AkkaraArtificial intelligence (AI) has revolutionized ophthalmology by aiding in the diagnosis, prognosis, and treatment planning of various eye diseases. However, AI’s potential extends beyond ocular conditions. By analyzing eye-related biomarkers, AI can utilize the eye as a window into the body’s systemic health. This field, known as oculomics, leverages AI and deep learning algorithms to process vast amounts of data from imaging techniques such as fundus photography, optical coherence tomography (OCT), OCT angiography, infrared iris imaging, slit-lamp photography, and external eye photography. AI-powered analysis of these images can predict systemic diseases such as Alzheimer’s, Parkinson’s, cardiovascular disease, cerebrovascular disease, chronic kidney disease, and liver disease. Retinal changes —including alterations in the retinal nerve fiber layer, ganglion cell layer, and retinal vessels —serve as valuable indicators of these conditions. Additionally, AI can estimate age, sex, body composition, and other health parameters from eye images. While the potential of AI in oculomics is promising, challenges such as access to ophthalmic imaging, data quality, and the need for rigorous validation must be addressed to ensure its widespread adoption and clinical utility. Nevertheless, AI holds the potential to transform healthcare by enabling early detection, noninvasive screening, and personalized treatment for a wide range of systemic diseases.https://journals.lww.com/10.4103/kjo.kjo_124_24agealzheimersartificial intelligencecardiovascular diseasecerebrovascular diseasecognitive impairmentdiabetesgenderkidney diseaseliver diseasemachine learningoctparkinsonssystemic diseases
spellingShingle John Davis Akkara
Retinal revelations: Seeing beyond the eye with artificial intelligence
Kerala Journal of Ophthalmology
age
alzheimers
artificial intelligence
cardiovascular disease
cerebrovascular disease
cognitive impairment
diabetes
gender
kidney disease
liver disease
machine learning
oct
parkinsons
systemic diseases
title Retinal revelations: Seeing beyond the eye with artificial intelligence
title_full Retinal revelations: Seeing beyond the eye with artificial intelligence
title_fullStr Retinal revelations: Seeing beyond the eye with artificial intelligence
title_full_unstemmed Retinal revelations: Seeing beyond the eye with artificial intelligence
title_short Retinal revelations: Seeing beyond the eye with artificial intelligence
title_sort retinal revelations seeing beyond the eye with artificial intelligence
topic age
alzheimers
artificial intelligence
cardiovascular disease
cerebrovascular disease
cognitive impairment
diabetes
gender
kidney disease
liver disease
machine learning
oct
parkinsons
systemic diseases
url https://journals.lww.com/10.4103/kjo.kjo_124_24
work_keys_str_mv AT johndavisakkara retinalrevelationsseeingbeyondtheeyewithartificialintelligence