Anticarcinogenic effects of ursodeoxycholic acid in pancreatic adenocarcinoma cell models

Anticarcinogenic effects of ursodeoxycholic acid in pancreatic adenocarcinoma cell models

Changes to the composition of the microbiome in neoplasia, is termed oncobiosis, may affect tumor behavior through the changes to the secretion of bacterial metabolites. In this study we show, that ursodeoxycholic acid (UDCA), a bacterial metabolite, has cytostatic properties in pancreatic adenocarc...

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Bibliographic Details
Main Authors: Patrik Kovács, Szandra Schwarcz, Petra Nyerges, Tímea Ingrid Bíró, Gyula Ujlaki, Péter Bai, Edit Mikó
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
ursodeoxycholic acid
bile acid
epithelial mesenchymal transition
oxidative stress
cancer stem cell
oxidative phosphorylation
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2024.1487685/full
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https://www.frontiersin.org/articles/10.3389/fcell.2024.1487685/full

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