Alleviatory Role of Panax Notoginseng Saponins in Modulating Inflammation and Pulmonary Vascular Remodeling in Chronic Obstructive Pulmonary Disease: mechanisms and Implications

Alleviatory Role of Panax Notoginseng Saponins in Modulating Inflammation and Pulmonary Vascular Remodeling in Chronic Obstructive Pulmonary Disease: mechanisms and Implications

COPD is an inflammatory lung disease that limits airflow and remodels the pulmonary vascular system. This study delves into the therapeutic potential and mechanistic underpinnings of Panax notoginseng Saponins (PNS) in alleviating inflammation and pulmonary vascular remodeling in a COPD rat model. S...

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Bibliographic Details
Main Authors: Yanan Hu, Qiuyang Fan, Bo Qiao, Ou Xu, Bijun Lv, Niping Han, Xiaomei Zhang
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:COPD
Subjects:
Chronic obstructive pulmonary disease
panax notoginseng saponins
inflammation
vascular remodeling
TLR4/NF-κB/HIF-1α/VEGF pathway
network pharmacology
Online Access:https://www.tandfonline.com/doi/10.1080/15412555.2024.2329282
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