Alpha, Beta- Unsaturated Lactone-Nitrone Cycloadditions: a Route to the Synthesis of (±)–Tussilagin

Reaction of nitrone (V with a, f1 -unsaturated lactone C.4) resulted in the isolation of a single adduct (7). The observed high regiochemical control has encouraged further explorations of natural product synthesis. A route to the synthesis of an interesting member of Pyrrolizidine- Alkaloid family;...

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Bibliographic Details
Main Author: Mohammed A. Al-Nuri
Format: Article
Language:English
Published: An-Najah National University 1994-09-01
Series:مجلة جامعة النجاح للأبحاث العلوم الطبيعية
Online Access:https://journals.najah.edu/media/journals/full_texts/unsaturated-lactone-nitrone-cycloadditions-route-synthesis-tussilagin.pdf
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Summary:Reaction of nitrone (V with a, f1 -unsaturated lactone C.4) resulted in the isolation of a single adduct (7). The observed high regiochemical control has encouraged further explorations of natural product synthesis. A route to the synthesis of an interesting member of Pyrrolizidine- Alkaloid family; (±) -Tussilagin 90/ has been described.
ISSN:1727-2114
2311-8865