Matrix-induced nuclear remodeling and mechano-therapeutics

Summary: The extracellular matrix (ECM) provides structural support and mechanical cues that profoundly influence cellular behavior via nuclear mechanotransduction. This review discusses how ECM biophysical properties, including stiffness, topology, and spatial confinement, regulate nuclear mechanic...

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Bibliographic Details
Main Authors: Jung-Hwan Lee, Yeo Gyun Yun, Hae-Won Kim
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Cell Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725009477
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