Veratridine Induces Vasorelaxation in Mouse Cecocolic Mesenteric Arteries

Veratridine Induces Vasorelaxation in Mouse Cecocolic Mesenteric Arteries

The vegetal alkaloid toxin veratridine (VTD) is a selective voltage-gated Na<sup>+</sup> (Na<sub>V</sub>) channel activator, widely used as a pharmacological tool in vascular physiology. We have previously shown that Na<sub>V</sub> channels, expressed in arteries,...

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Main Authors: Joohee Park, Christina Sahyoun, Jacinthe Frangieh, Léa Réthoré, Coralyne Proux, Linda Grimaud, Emilie Vessières, Jennifer Bourreau, César Mattei, Daniel Henrion, Céline Marionneau, Ziad Fajloun, Claire Legendre, Christian Legros
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Toxins
Subjects:
veratridine
voltage-gated Na<sup>+</sup> channel
Na<sup>+</sup>/Ca<sup>2+</sup> exchanger (NCX)
mouse mesenteric arteries
myography
mesenteric and endothelial cell lines
Online Access:https://www.mdpi.com/2072-6651/16/12/533
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