The PRIMERO birth cohort: Design and baseline characteristics

The PRIMERO birth cohort: Design and baseline characteristics

Background: Although early-life respiratory illnesses (RIs) are linked to childhood asthma, it is unclear whether children are predisposed to both conditions or if RIs induce alterations that lead to asthma. Puerto Rican children, who bear a disproportionate burden of early-life RIs and asthma, are...

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Main Authors: Jonathan I. Witonsky, MD, MAS, Jennifer R. Elhawary, MS, Celeste Eng, BS, Sam S. Oh, PhD, MPH, Sandra Salazar, Maria G. Contreras, BS, Vivian Medina, RN, BSN, SC, Elizabeth A. Secor, MA, Priscilla Zhang, BS, Jamie L. Everman, PhD, Ana Fairbanks-Mahnke, BS, Elmar Pruesse, PhD, Satria P. Sajuthi, PhD, Chih-Hao Chang, PhD, MPH, Tsunami Rosado Guerrero, BS, Keyshla Canales Fuentes, BS, Natalie Lopez, MD, Chris Angely Montañez-López, MS, Emily Vazquez Morales, MD, Nicole Vazquez Morales, MD, Richeliz Alfonso Otero, MD, Raymarie Colon Rivera, BS, Leysha Rodriguez, BA, Gabriela Vazquez, BS, Donglei Hu, PhD, Scott Huntsman, MS, Nathan D. Jackson, PhD, Yingchun Li, MD, PhD, Andrew Morin, MA, Natalie A. Nieves, BS, Cydney Rios, BS, Gonzalo Serrano, BS, Blake J.M. Williams, MS, Elad Ziv, MD, Camille M. Moore, PhD, Dean Sheppard, MD, Esteban González Burchard, MD, MPH, Max A. Seibold, PhD, Jose R. Rodríguez-Santana, MD
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Journal of Allergy and Clinical Immunology: Global
Subjects:
Childhood asthma
respiratory illness
birth cohort
gene–environment interactions
transcriptomics
viral pathogen detection
Online Access:http://www.sciencedirect.com/science/article/pii/S2772829325000712
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