ENHANCE THE AQUEOUS SOLUBILITY OF DICLOFENAC THROUGH THE SYNTHESIS OF DICLOFENAC-INOSITOL PRODRUG

ENHANCE THE AQUEOUS SOLUBILITY OF DICLOFENAC THROUGH THE SYNTHESIS OF DICLOFENAC-INOSITOL PRODRUG

Due to limited aqueous solubility, poor bioavailability makes oral dosage formulations difficult to formulate. Chemical alteration of medicinal compounds improves solubility. Prodrug design is a popular molecular modification method that improves solubility and oral bioavailability. This study aims...

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Bibliographic Details
Main Authors: Hemn Latif Qader, Omar Abdulrahman alsheikhly, Hewa Abdulla Hamadameen Hama, Adnan Burhan Qader
Format: Article
Language:English
Published: University of Zakho 2024-11-01
Series:Science Journal of University of Zakho
Subjects:
Aqueous solubility
Diclofenac
esterification reaction
inositol
prodrug
Online Access:http://sjuoz.uoz.edu.krd/index.php/sjuoz/article/view/1360
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http://sjuoz.uoz.edu.krd/index.php/sjuoz/article/view/1360

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