Enhancing radiotherapy in triple-negative breast cancer with hesperetin-induced ferroptosis via AURKA targeting nanocomposites

Enhancing radiotherapy in triple-negative breast cancer with hesperetin-induced ferroptosis via AURKA targeting nanocomposites

Abstract Triple-negative breast cancer (TNBC) is an aggressive cancer type that lacks targeted treatment options. Ferroptosis, a novel therapeutic strategy, induces cell death by disrupting the oxidative-reductive balance. Hesperetin, a potential TNBC therapeutic drug, has unidentified regulatory ta...

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Bibliographic Details
Main Authors: Yang Guo, Huan Wang, Xinlei Wang, Keyan Chen, Liang Feng
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Journal of Nanobiotechnology
Subjects:
Triple-negative breast cancer
Ferroptosis
Hesperetin
AURKA
Redox homeostasis
Radiotherapy efficacy
Online Access:https://doi.org/10.1186/s12951-024-02987-3
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https://doi.org/10.1186/s12951-024-02987-3

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