Near extinction of the HBV quasispecies driven by the hard selective sweep in chronic hepatitis B

Near extinction of the HBV quasispecies driven by the hard selective sweep in chronic hepatitis B

ABSTRACT The viral quasispecies play an important role in pathogenesis. However, little is known about the nature of hepatitis B virus (HBV) quasispecies and its impact on the outcomes of chronic hepatitis B. Here, we characterized the bona fide quasispecies viral populations from 16 chronically inf...

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Bibliographic Details
Main Authors: Daiqiang Lu, Andong He, Guichan Liao, Renyu Zhou, Zichun Cheng, Ka Cheuk Yip, Xiufang Wang, Wei Cao, Jiaojiao Peng, Ruiman Li, Jie Peng, Feng Gao
Format: Article
Language:English
Published: American Society for Microbiology 2025-08-01
Series:mBio
Subjects:
hepatitis B virus
evolution
selection
escape
diversity
Online Access:https://journals.asm.org/doi/10.1128/mbio.01113-25
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https://journals.asm.org/doi/10.1128/mbio.01113-25

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