E2F1 suppresses Epstein-Barr virus lytic reactivation through cellular and viral transcriptional networks.
Epstein-Barr virus (EBV) establishes life-long persistence infection displaying a biphasic viral life cycle - latent phase and lytic replication. While latent EBV infection is linked to several B- and epithelial cell malignancies, periodic lytic-cycle reactivation is crucial for maintaining viral pr...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2025-08-01
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| Series: | PLoS Pathogens |
| Online Access: | https://doi.org/10.1371/journal.ppat.1013410 |
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