miR-1275 Delivered via Mesenchymal Stem Cell-Derived Extracellular Vesicles Regulates ER-Phagy Through AXIN2 in Nucleus Pulposus Cells

miR-1275 Delivered via Mesenchymal Stem Cell-Derived Extracellular Vesicles Regulates ER-Phagy Through AXIN2 in Nucleus Pulposus Cells

Intervertebral disc degeneration (IDD) is a major contributor to low back pain, a prevalent and debilitating condition. Nucleus pulposus (NP) cells are essential for maintaining disc homeostasis, and their dysfunction plays a crucial role in IDD development. This study aimed to explore the potential...

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Bibliographic Details
Main Authors: Zhiwu Dong, Hailong Zhang, Wenwei Yang, Keliang Huang, Xin Zhang, Lianxiang Xing, Ying Zhang, Kewen Zhao
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/sci/5091529
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