Pericytes promote metastasis by regulating tumor local vascular tone and hemodynamics

Pericytes promote metastasis by regulating tumor local vascular tone and hemodynamics

Abstract Hemodynamics are important for survival and extravasation of circulating tumor cells, whereas the effects of hemodynamics on tumor cell intravasation remain mostly unknown. Here, we show that colorectal cancer patients with liver metastasis are characterized by increased diameter and blood...

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Main Authors: Xiaobo Li, Sishan Yan, Xiaoyu Wu, Qun Miao, Dong Zhang, Wenfeng Mai, Shuai Han, Zhongshun Tang, Mingfang Ye, Shuo Zhang, Ji-an Wei, Jinghua Pan, Dandan Huang, Shenghui Qiu, Zhan Zhao, Xiaotong Zhong, Maohua Huang, Ming Qi, Junqiu Zhang, Chenran Wang, Jingwen Xie, Sheng Wang, Oscar Junhong Luo, Dongmei Zhang, Wencai Ye, Minfeng Chen
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62475-6
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https://doi.org/10.1038/s41467-025-62475-6

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