Rapidly Progressive Pulmonary Fibrosis in a Patient Treated with Danazol for Idiopathic Thrombocytopenic Purpura

The case of a patient that developed pulmonary fibrosis two months after initiation of danazol for treatment of idiopathic thrombocytopenic purpura is described. Bilateral pneumothoraxes and pneumomediastinum complicated the rapidly fatal pulmonary fibrosis. An association between danazol therapy an...

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Main Authors: Smita Pakhale, Yuri Moltyaner, Dean Chamberlain, Neil Lazar
Format: Article
Language:English
Published: Wiley 2004-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/2004/935458
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author Smita Pakhale
Yuri Moltyaner
Dean Chamberlain
Neil Lazar
author_facet Smita Pakhale
Yuri Moltyaner
Dean Chamberlain
Neil Lazar
author_sort Smita Pakhale
collection DOAJ
description The case of a patient that developed pulmonary fibrosis two months after initiation of danazol for treatment of idiopathic thrombocytopenic purpura is described. Bilateral pneumothoraxes and pneumomediastinum complicated the rapidly fatal pulmonary fibrosis. An association between danazol therapy and the development of pulmonary fibrosis is suspected. There is only one other case report with this connection in the literature.
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institution Kabale University
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spelling doaj-art-c44c89f68dbc44f89cebf9788cb11e232025-02-03T05:47:24ZengWileyCanadian Respiratory Journal1198-22412004-01-01111555710.1155/2004/935458Rapidly Progressive Pulmonary Fibrosis in a Patient Treated with Danazol for Idiopathic Thrombocytopenic PurpuraSmita Pakhale0Yuri Moltyaner1Dean Chamberlain2Neil Lazar3Departments of Respirology, Toronto General Hospital, Toronto, Ontario, CanadaDepartments of Respirology, Toronto General Hospital, Toronto, Ontario, CanadaDepartment of Pathology, Toronto General Hospital, Toronto, Ontario, CanadaDepartments of Respirology, Toronto General Hospital, Toronto, Ontario, CanadaThe case of a patient that developed pulmonary fibrosis two months after initiation of danazol for treatment of idiopathic thrombocytopenic purpura is described. Bilateral pneumothoraxes and pneumomediastinum complicated the rapidly fatal pulmonary fibrosis. An association between danazol therapy and the development of pulmonary fibrosis is suspected. There is only one other case report with this connection in the literature.http://dx.doi.org/10.1155/2004/935458
spellingShingle Smita Pakhale
Yuri Moltyaner
Dean Chamberlain
Neil Lazar
Rapidly Progressive Pulmonary Fibrosis in a Patient Treated with Danazol for Idiopathic Thrombocytopenic Purpura
Canadian Respiratory Journal
title Rapidly Progressive Pulmonary Fibrosis in a Patient Treated with Danazol for Idiopathic Thrombocytopenic Purpura
title_full Rapidly Progressive Pulmonary Fibrosis in a Patient Treated with Danazol for Idiopathic Thrombocytopenic Purpura
title_fullStr Rapidly Progressive Pulmonary Fibrosis in a Patient Treated with Danazol for Idiopathic Thrombocytopenic Purpura
title_full_unstemmed Rapidly Progressive Pulmonary Fibrosis in a Patient Treated with Danazol for Idiopathic Thrombocytopenic Purpura
title_short Rapidly Progressive Pulmonary Fibrosis in a Patient Treated with Danazol for Idiopathic Thrombocytopenic Purpura
title_sort rapidly progressive pulmonary fibrosis in a patient treated with danazol for idiopathic thrombocytopenic purpura
url http://dx.doi.org/10.1155/2004/935458
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AT deanchamberlain rapidlyprogressivepulmonaryfibrosisinapatienttreatedwithdanazolforidiopathicthrombocytopenicpurpura
AT neillazar rapidlyprogressivepulmonaryfibrosisinapatienttreatedwithdanazolforidiopathicthrombocytopenicpurpura