In Vivo Dosimetry in Radiotherapy: Techniques, Applications, and Future Directions

In vivo dosimetry (IVD) is a vital component of modern radiotherapy, ensuring accurate and safe delivery of radiation doses to patients by measuring dose parameters during treatment. This paper provides a comprehensive overview of IVD, covering its fundamental principles, historical development, and...

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Main Authors: James C. L. Chow, Harry E. Ruda
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Encyclopedia
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Online Access:https://www.mdpi.com/2673-8392/5/1/40
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author James C. L. Chow
Harry E. Ruda
author_facet James C. L. Chow
Harry E. Ruda
author_sort James C. L. Chow
collection DOAJ
description In vivo dosimetry (IVD) is a vital component of modern radiotherapy, ensuring accurate and safe delivery of radiation doses to patients by measuring dose parameters during treatment. This paper provides a comprehensive overview of IVD, covering its fundamental principles, historical development, and the technologies used in clinical practice. Key techniques, including thermoluminescent dosimeters (TLDs), optically stimulated luminescent dosimeters (OSLDs), diodes, metal-oxide-semiconductor field-effect transistors (MOSFETs), and electronic portal imaging devices (EPIDs), are discussed, highlighting their clinical applications, advantages, and limitations. The role of IVD in external beam radiotherapy, brachytherapy, and pediatric treatments is emphasized, particularly its contributions to quality assurance, treatment validation, and error mitigation. Challenges such as measurement uncertainties, technical constraints, and integration into clinical workflows are explored, along with potential solutions and emerging innovations. The paper also addresses future perspectives, including advancements in artificial intelligence, adaptive radiotherapy, and personalized dosimetry systems. This entry underscores the critical role of IVD in enhancing the precision and reliability of radiotherapy, advocating for ongoing research and technological development.
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spelling doaj-art-c3d02bff61a24e86bcb3dcf437cd7f2a2025-08-20T03:43:36ZengMDPI AGEncyclopedia2673-83922025-03-01514010.3390/encyclopedia5010040In Vivo Dosimetry in Radiotherapy: Techniques, Applications, and Future DirectionsJames C. L. Chow0Harry E. Ruda1Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1X6, CanadaDepartment of Materials Science and Engineering, University of Toronto, Toronto, ON M5S 3E4, CanadaIn vivo dosimetry (IVD) is a vital component of modern radiotherapy, ensuring accurate and safe delivery of radiation doses to patients by measuring dose parameters during treatment. This paper provides a comprehensive overview of IVD, covering its fundamental principles, historical development, and the technologies used in clinical practice. Key techniques, including thermoluminescent dosimeters (TLDs), optically stimulated luminescent dosimeters (OSLDs), diodes, metal-oxide-semiconductor field-effect transistors (MOSFETs), and electronic portal imaging devices (EPIDs), are discussed, highlighting their clinical applications, advantages, and limitations. The role of IVD in external beam radiotherapy, brachytherapy, and pediatric treatments is emphasized, particularly its contributions to quality assurance, treatment validation, and error mitigation. Challenges such as measurement uncertainties, technical constraints, and integration into clinical workflows are explored, along with potential solutions and emerging innovations. The paper also addresses future perspectives, including advancements in artificial intelligence, adaptive radiotherapy, and personalized dosimetry systems. This entry underscores the critical role of IVD in enhancing the precision and reliability of radiotherapy, advocating for ongoing research and technological development.https://www.mdpi.com/2673-8392/5/1/40In vivo dosimetrypatient safetyradiotherapythermoluminescent dosimetersoptically stimulated luminescent dosimetersdiodes
spellingShingle James C. L. Chow
Harry E. Ruda
In Vivo Dosimetry in Radiotherapy: Techniques, Applications, and Future Directions
Encyclopedia
In vivo dosimetry
patient safety
radiotherapy
thermoluminescent dosimeters
optically stimulated luminescent dosimeters
diodes
title In Vivo Dosimetry in Radiotherapy: Techniques, Applications, and Future Directions
title_full In Vivo Dosimetry in Radiotherapy: Techniques, Applications, and Future Directions
title_fullStr In Vivo Dosimetry in Radiotherapy: Techniques, Applications, and Future Directions
title_full_unstemmed In Vivo Dosimetry in Radiotherapy: Techniques, Applications, and Future Directions
title_short In Vivo Dosimetry in Radiotherapy: Techniques, Applications, and Future Directions
title_sort in vivo dosimetry in radiotherapy techniques applications and future directions
topic In vivo dosimetry
patient safety
radiotherapy
thermoluminescent dosimeters
optically stimulated luminescent dosimeters
diodes
url https://www.mdpi.com/2673-8392/5/1/40
work_keys_str_mv AT jamesclchow invivodosimetryinradiotherapytechniquesapplicationsandfuturedirections
AT harryeruda invivodosimetryinradiotherapytechniquesapplicationsandfuturedirections