Reprogramming the melanoma and immunosuppressive myeloid cells with esomeprazole-loaded PLGA nanoparticles

Reprogramming the melanoma and immunosuppressive myeloid cells with esomeprazole-loaded PLGA nanoparticles

Summary: Proton pump inhibitors have been explored for potentiating cancer therapies via reverting the tumor acidity and promoting the activation of anti-tumor immune responses. To regulate the intracellular pH of melanoma and immunosuppressive myeloid cells, we developed poly(L-lactide-co-glycolide...

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Main Authors: Nicola Cerioli, Wissem Bououdina, Alessandro Mereu, Evangelos Natsaridis, Jeannette Salsetta, Agata Cova, Gianpiero Lupoli, Elisa D’Angelo, Licia Rivoltini, Carl G. Figdor, Veronica Huber, Oya Tagit
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:iScience
Subjects:
Biological sciences
Biotechnology
Immunology
Medical biotechnology
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422402786X
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http://www.sciencedirect.com/science/article/pii/S258900422402786X

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