Comparative analysis of physicochemical properties, bioequivalence, safety and tolerability of the first domestic semaglutide

Comparative analysis of physicochemical properties, bioequivalence, safety and tolerability of the first domestic semaglutide

Semaglutide is a representative of analogues of the incretin hormone human glucagon-like peptide-1 (GLP-1) and is currently used in Russia for the treatment of type 2 diabetes mellitus (T2DM; in monotherapy and in combination therapy), including patients with obesity and overweight.The aim of the wo...

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Main Authors: A. S. Ametov, I. E. Shokhin, E. A. Rogozhina, T. G. Bodrova, M. E. Nevretdinova, P. A. Bely, K. Ya. Zaslavskaya, V. S. Scherbakova, D. V. Kurkin, K. N. Koryanova, E. S. Mishchenko, E. Yu. Kesova, E. D. Kozlov, E. S. Samoshkina, D. N. Andreev, Yu. G. Kazaishvili, S. M. Noskov, L. A. Balykova
Format: Article
Language:Russian
Published: Volgograd State Medical University, Pyatigorsk Medical and Pharmaceutical Institute 2024-01-01
Series:Фармация и фармакология (Пятигорск)
Subjects:
glucagon-like peptide-1
glp-1
bioequivalence
pharmacokinetics
semaglutide
type 2 diabetes mellitus
physicochemical properties
safety profile
biological activity
Online Access:https://www.pharmpharm.ru/jour/article/view/1385
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