Clinical outcomes of a digital musculoskeletal women’s pelvic health program: an observational, longitudinal study with comparison group

Abstract Background Chronic pelvic pain is a common yet undertreated condition that significantly impacts quality of life for women worldwide. Digital exercise therapy designed to target pelvic pain can improve symptomology while reducing time and cost-related barriers to in-person clinical care. Me...

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Main Authors: Mindy Hong, Rachel Foster Kirk, Bijal Toprani, Cynthia Castro Sweet, Clare Pan, Jeffrey Krauss, Tamara Grisales
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Women's Health
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Online Access:https://doi.org/10.1186/s12905-024-03475-4
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author Mindy Hong
Rachel Foster Kirk
Bijal Toprani
Cynthia Castro Sweet
Clare Pan
Jeffrey Krauss
Tamara Grisales
author_facet Mindy Hong
Rachel Foster Kirk
Bijal Toprani
Cynthia Castro Sweet
Clare Pan
Jeffrey Krauss
Tamara Grisales
author_sort Mindy Hong
collection DOAJ
description Abstract Background Chronic pelvic pain is a common yet undertreated condition that significantly impacts quality of life for women worldwide. Digital exercise therapy designed to target pelvic pain can improve symptomology while reducing time and cost-related barriers to in-person clinical care. Methods This longitudinal, observational study of a digital women’s pelvic health program examined pelvic pain, anxiety, and depression at 4 and 12 weeks in female adults experiencing chronic pelvic pain. Intervention participants received a digital pelvic health program including personalized exercise therapy sessions, health education articles, and health coaching. A comparison group of nonparticipants received a series of education articles related to pelvic health. Data were collected at baseline, 4 and 12 weeks. Unadjusted and adjusted linear mixed effects models were conducted to model changes in clinical outcomes over time. Results A total of 797 participants (intervention: 495, nonparticipants: 302) were included in the sample. Baseline mean (SD) age was 41.5 (11.7) years and mean pain was 45.7 (18.5) out of 100. Compared to baseline, the intervention group showed significantly more pain improvement at 4 and 12 weeks versus nonparticipants after adjusting for baseline factors. The intervention group’s pain scores decreased by 44.5% at 4 weeks and 53.6% at 12 weeks. The intervention group’s adjusted pain scores decreased from 42.0 (95% CI: [39.4, 44.7]) at baseline to 23.3 (95% CI: [20.5, 26.2]) at 4 weeks to 19.5 (95% CI: [16.7, 22.4]) at 12 weeks. In contrast, nonparticipants’ pain scores decreased by 21.6% at 4 weeks and 32.7% at 12 weeks. Nonparticipants’ adjusted pain scores decreased from 42.1 (95% CI: [38.4, 45.9]) at baseline to 33.0 (95% CI: [29.2, 36.8]) at 4 weeks to 28.3 (95% CI: [24.5, 32.2]) at 12 weeks. After adjustments, the probability of the intervention group screening for moderate or severe depression was significantly lower by 11.0% at 12 weeks versus nonparticipants. There were no significant differences in anxiety outcomes between groups at baseline, week 4, or week 12.  Conclusions A digital women’s pelvic health program may help reduce short-term pelvic pain and depression symptoms. Trial registration The WIRB-Copernicus Group Institutional Review Board (registration number IRB20234932) approved this study on November 6, 2023.
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spelling doaj-art-c337ffb60f9d484d923a93de2a6af6102025-01-12T12:38:08ZengBMCBMC Women's Health1472-68742025-01-0125111110.1186/s12905-024-03475-4Clinical outcomes of a digital musculoskeletal women’s pelvic health program: an observational, longitudinal study with comparison groupMindy Hong0Rachel Foster Kirk1Bijal Toprani2Cynthia Castro Sweet3Clare Pan4Jeffrey Krauss5Tamara Grisales6Hinge Health, IncHinge Health, IncHinge Health, IncHinge Health, IncHinge Health, IncHinge Health, IncHinge Health, IncAbstract Background Chronic pelvic pain is a common yet undertreated condition that significantly impacts quality of life for women worldwide. Digital exercise therapy designed to target pelvic pain can improve symptomology while reducing time and cost-related barriers to in-person clinical care. Methods This longitudinal, observational study of a digital women’s pelvic health program examined pelvic pain, anxiety, and depression at 4 and 12 weeks in female adults experiencing chronic pelvic pain. Intervention participants received a digital pelvic health program including personalized exercise therapy sessions, health education articles, and health coaching. A comparison group of nonparticipants received a series of education articles related to pelvic health. Data were collected at baseline, 4 and 12 weeks. Unadjusted and adjusted linear mixed effects models were conducted to model changes in clinical outcomes over time. Results A total of 797 participants (intervention: 495, nonparticipants: 302) were included in the sample. Baseline mean (SD) age was 41.5 (11.7) years and mean pain was 45.7 (18.5) out of 100. Compared to baseline, the intervention group showed significantly more pain improvement at 4 and 12 weeks versus nonparticipants after adjusting for baseline factors. The intervention group’s pain scores decreased by 44.5% at 4 weeks and 53.6% at 12 weeks. The intervention group’s adjusted pain scores decreased from 42.0 (95% CI: [39.4, 44.7]) at baseline to 23.3 (95% CI: [20.5, 26.2]) at 4 weeks to 19.5 (95% CI: [16.7, 22.4]) at 12 weeks. In contrast, nonparticipants’ pain scores decreased by 21.6% at 4 weeks and 32.7% at 12 weeks. Nonparticipants’ adjusted pain scores decreased from 42.1 (95% CI: [38.4, 45.9]) at baseline to 33.0 (95% CI: [29.2, 36.8]) at 4 weeks to 28.3 (95% CI: [24.5, 32.2]) at 12 weeks. After adjustments, the probability of the intervention group screening for moderate or severe depression was significantly lower by 11.0% at 12 weeks versus nonparticipants. There were no significant differences in anxiety outcomes between groups at baseline, week 4, or week 12.  Conclusions A digital women’s pelvic health program may help reduce short-term pelvic pain and depression symptoms. Trial registration The WIRB-Copernicus Group Institutional Review Board (registration number IRB20234932) approved this study on November 6, 2023.https://doi.org/10.1186/s12905-024-03475-4Exercise therapyPelvic painWomen’s healthMusculoskeletal painTelemedicineTelerehabilitation
spellingShingle Mindy Hong
Rachel Foster Kirk
Bijal Toprani
Cynthia Castro Sweet
Clare Pan
Jeffrey Krauss
Tamara Grisales
Clinical outcomes of a digital musculoskeletal women’s pelvic health program: an observational, longitudinal study with comparison group
BMC Women's Health
Exercise therapy
Pelvic pain
Women’s health
Musculoskeletal pain
Telemedicine
Telerehabilitation
title Clinical outcomes of a digital musculoskeletal women’s pelvic health program: an observational, longitudinal study with comparison group
title_full Clinical outcomes of a digital musculoskeletal women’s pelvic health program: an observational, longitudinal study with comparison group
title_fullStr Clinical outcomes of a digital musculoskeletal women’s pelvic health program: an observational, longitudinal study with comparison group
title_full_unstemmed Clinical outcomes of a digital musculoskeletal women’s pelvic health program: an observational, longitudinal study with comparison group
title_short Clinical outcomes of a digital musculoskeletal women’s pelvic health program: an observational, longitudinal study with comparison group
title_sort clinical outcomes of a digital musculoskeletal women s pelvic health program an observational longitudinal study with comparison group
topic Exercise therapy
Pelvic pain
Women’s health
Musculoskeletal pain
Telemedicine
Telerehabilitation
url https://doi.org/10.1186/s12905-024-03475-4
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