Rutin and Glimepiride Combination: A Novel Approach for Managing Diabetes Nephropathy in Streptozotocin Induced Diabetes in Wistar Rats

Rutin and Glimepiride Combination: A Novel Approach for Managing Diabetes Nephropathy in Streptozotocin Induced Diabetes in Wistar Rats

Background: Diabetes mellitus remains a global health concern, because of its associated complications, including diabetic nephropathy. Glimepiride, a sulfonylurea derivative, and rutin, a flavonoid with antioxidant properties, have shown potential in managing diabetic complications. This study was...

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Main Authors: Vinod A. Bairagi, Shekhar D. Jagtap, Swapnil B. Jadhav, Smruti R. Jadhav, Yogesh S. Ahire
Format: Article
Language:English
Published: Compuscript Ltd 2024-11-01
Series:BIO Integration
Subjects:
diabetic nephropathy
glimepiride
histopathology
inflammatory cytokines
oxidative stress
rats
renal hypertrophy
rutin
streptozotocin
synergistic effects
Online Access:https://www.scienceopen.com/hosted-document?doi=10.15212/bioi-2024-0037
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https://www.scienceopen.com/hosted-document?doi=10.15212/bioi-2024-0037

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