Novel Lipid-Based Carriers of Provitamin D<sub>3</sub>: Synthesis and Spectroscopic Characterization of Acylglycerol Conjugated with 7-Dehydrocholesterol Residue and Its Glycerophospholipid Analogue

Novel Lipid-Based Carriers of Provitamin D<sub>3</sub>: Synthesis and Spectroscopic Characterization of Acylglycerol Conjugated with 7-Dehydrocholesterol Residue and Its Glycerophospholipid Analogue

The aim of this research was to design and synthesize new lipid conjugates of 7-DHC that could serve as a new storage form of esterified provitamin D<sub>3</sub>, increasing the reservoir of this biomolecule in the epidermis and enabling controlled production of vitamin D<sub>3<...

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Bibliographic Details
Main Authors: Witold Gładkowski, Susanna Ortlieb, Natalia Niezgoda, Anna Chojnacka, Paulina Fortuna, Paweł Wiercik
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Molecules
Subjects:
lipid prodrugs
7-dehydrocholesterol
modified acylglycerols
modified phospholipids
succinate linker
acyl migration
Online Access:https://www.mdpi.com/1420-3049/29/23/5805
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