Quercetin alleviates ulcerative colitis through inhibiting CXCL8-CXCR1/2 axis: a network and transcriptome analysis

Quercetin alleviates ulcerative colitis through inhibiting CXCL8-CXCR1/2 axis: a network and transcriptome analysis

IntroductionUlcerative colitis (UC) is a chronic inflammatory condition of the intestinal tract in which mucosal healing is a crucial measure of therapeutic efficacy. Quercetin, a flavonoid prevalent in various foods and traditional Chinese medicines, exhibits notable pharmacological properties, inc...

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Main Authors: Zhangyu Jiang, Mingjuan Yan, Yanmi Qin, Zhenglin Liu, Yilin Duan, Yingju Wang, Ruisen Zhang, Wenjia Lin, Yanwu Li, Tian Xie, Junyu Ke
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Pharmacology
Subjects:
ulcerative colitis
quercetin
network analysis
intestinal mucosal barrier
transcriptome
CXCL8-CXCR1/2 axis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1485255/full
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https://www.frontiersin.org/articles/10.3389/fphar.2024.1485255/full

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