Oral varespladib for the treatment of snakebite envenoming in India and the USA (BRAVO): a phase II randomised clinical trial

Oral varespladib for the treatment of snakebite envenoming in India and the USA (BRAVO): a phase II randomised clinical trial

Introduction Snakebite envenoming (SBE) results in over 500 000 deaths or disabling injuries annually. Varespladib methyl, an oral inhibitor of secretory phospholipase A2, is a nearly ubiquitous component of snake venoms. We conducted a phase II clinical trial to assess efficacy and safety of oral v...

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Main Authors: Chanaveerappa Bammigatti, Timothy F Platts-Mills, Ashish Bhalla, Harish Kumar, Matthew R Lewin, Surendra Kumar, Charles J Gerardo, Rebecca W Carter, Farshad M Shirazi, Suneetha D Kotehal, Peter D Akpunonu, Richard B Schwartz, Neeraj Manikath, Partha P Mukherjee, Thomas C Arnold, Brian J Wolk, Sophia S Sheikh, Dawn R Sollee, David J Vearrier, Samuel J Francis, Adiel Aizenberg, Madhu K Ravikumar, Sujoy Sarkar, Taylor Haston, Andrew Micciche, Suraj C Oomman, Jeffery L Owen, Brandi A Ritter, Stephen P Samuel
Format: Article
Language:English
Published: BMJ Publishing Group 2024-10-01
Series:BMJ Global Health
Online Access:https://gh.bmj.com/content/9/10/e015985.full
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