Modeling antibody persistence after MenACYW-TT vaccination and comparative analysis with other quadrivalent meningococcal vaccines

Modeling antibody persistence after MenACYW-TT vaccination and comparative analysis with other quadrivalent meningococcal vaccines

Abstract Evaluating the persistence of antibody titers produced by quadrivalent meningococcal vaccines is crucial for determining the optimal timing for primary and booster doses. Using 3 − 7-year persistence data after a single priming dose of MenACYW-TT to fit a statistical model of antibody decay...

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Bibliographic Details
Main Authors: Laurent Coudeville, Isabelle Bertrand-Gerentes, Céline Zocchetti, Edith Langevin, Siham Bchir, Florence Coste, Philipp Oster
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Invasive meningococcal disease
Quadrivalent meningococcal vaccines
Serogroups A, C, W, Y
Long-term immunopersistence
Seroprotection
Modelling
Online Access:https://doi.org/10.1038/s41598-025-08112-0
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https://doi.org/10.1038/s41598-025-08112-0

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