Nanoalbumin–prodrug conjugates prepared via a thiolation‐and‐conjugation method improve cancer chemotherapy and immune checkpoint blockade therapy by promoting CD8+ T‐cell infiltration

Abstract Protein–drug conjugates are emerging tools to combat cancers. Here, we adopted an indirect thiolation‐and‐conjugation method as a general strategy to prepare protein–drug conjugates. We found for the first time that this method led to the formation of nanometric conjugates, probably due to...

Full description

Saved in:
Bibliographic Details
Main Authors: Long Chen, Nuo Xu, Pan Wang, Haichuan Zhu, Zijian Zhang, Zhanqun Yang, Wenyuan Zhang, Hongyan Guo, Jian Lin
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Bioengineering & Translational Medicine
Subjects:
Online Access:https://doi.org/10.1002/btm2.10377
Tags: Add Tag
No Tags, Be the first to tag this record!