Curcumin mediates glutathione depletion via metal–organic framework nanocarriers to enhance cisplatin chemosensitivity on esophageal cancer

Curcumin mediates glutathione depletion via metal–organic framework nanocarriers to enhance cisplatin chemosensitivity on esophageal cancer

Abstract Cisplatin (CDDP) is the primary drug used in the initial treatment of esophageal cancer (EC). However, its side effects and resistance can limit its effectiveness in clinical therapy. Curcumin (Cur)-mediated glutathione (GSH) depletion can reverse resistance, enhance the chemosensitivity of...

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Bibliographic Details
Main Authors: Yunhao Sun, Kaijun Ying, Jian Sun, Limin Qiu, Yao Wang, Mingming Ji, Lulu Zhou, Jinjin Chen
Format: Article
Language:English
Published: Springer 2024-12-01
Series:Discover Nano
Subjects:
Esophageal cancer
Cisplatin
Curcumin
Chemodynamic therapy
Nanoparticles
Online Access:https://doi.org/10.1186/s11671-024-04168-5
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https://doi.org/10.1186/s11671-024-04168-5

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