A Rare Case of Primary Bone Follicular Lymphoma with Multiple Osteolytic Lesions: A Case Report and Review of the Literature
<b>Introduction:</b> Primary bone lymphoma (PBL) is a rare clinical entity, accounting for less than 5% of all extranodal non-Hodgkin lymphomas and approximately 5% of primary bone tumors. Diffuse large B-cell lymphoma (DLBCL) is the most common histotype, accounting for about 80% of all...
Saved in:
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-09-01
|
| Series: | Hemato |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2673-6357/5/4/28 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1846104453420154880 |
|---|---|
| author | Chiara Togni Giacinto La Verde Sabrina Pelliccia Maria Paola Bianchi Arianna Di Napoli Tiziana Lanzolla Marta Zerunian Andrea Laghi Gianluca Maiorana Ambra Taglietti Agostino Tafuri |
| author_facet | Chiara Togni Giacinto La Verde Sabrina Pelliccia Maria Paola Bianchi Arianna Di Napoli Tiziana Lanzolla Marta Zerunian Andrea Laghi Gianluca Maiorana Ambra Taglietti Agostino Tafuri |
| author_sort | Chiara Togni |
| collection | DOAJ |
| description | <b>Introduction:</b> Primary bone lymphoma (PBL) is a rare clinical entity, accounting for less than 5% of all extranodal non-Hodgkin lymphomas and approximately 5% of primary bone tumors. Diffuse large B-cell lymphoma (DLBCL) is the most common histotype, accounting for about 80% of all PBL cases. Conversely, the incidence of indolent primary bone lymphomas (iPBL) represents less than 1% of all reported PBL cases, and data on these rarer lymphomas are scarce. Drawing on diagnostic criteria developed by the World Health Organization (WHO) and the International Extranodal Lymphoma Study Group (IELSG), we report a rare case of primary bone follicular lymphoma, focusing specifically on the clinical presentation and treatment. Discussion: Additionally, we provide a systematic review of the literature data on this very rare lymphoproliferative entity. |
| format | Article |
| id | doaj-art-c27cf523433f4c03b2cbe95a74c6f4e3 |
| institution | Kabale University |
| issn | 2673-6357 |
| language | English |
| publishDate | 2024-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Hemato |
| spelling | doaj-art-c27cf523433f4c03b2cbe95a74c6f4e32024-12-27T14:28:38ZengMDPI AGHemato2673-63572024-09-015438839510.3390/hemato5040028A Rare Case of Primary Bone Follicular Lymphoma with Multiple Osteolytic Lesions: A Case Report and Review of the LiteratureChiara Togni0Giacinto La Verde1Sabrina Pelliccia2Maria Paola Bianchi3Arianna Di Napoli4Tiziana Lanzolla5Marta Zerunian6Andrea Laghi7Gianluca Maiorana8Ambra Taglietti9Agostino Tafuri10Hematology, Department of Translational and Precision Medicine, Sapienza University, 00185 Rome, ItalyHematology Unit, Department of Clinical and Molecular Medicine, Sant’Andrea University Hospital, Sapienza University, 00189 Rome, ItalyHematology Unit, Department of Clinical and Molecular Medicine, Sant’Andrea University Hospital, Sapienza University, 00189 Rome, ItalyHematology Unit, Department of Clinical and Molecular Medicine, Sant’Andrea University Hospital, Sapienza University, 00189 Rome, ItalyPathology Unit, Department of Clinical and Molecular Medicine, Sant’Andrea University Hospital, Sapienza University, 00189 Rome, ItalyNuclear Medicine Unit, Department of Medical-Surgical Sciences and Translational Medicine, Sant’Andrea University Hospital, Sapienza University, 00189 Rome, ItalyRadiology Unit, Department of Medical-Surgical Sciences and Translational Medicine, Sant’Andrea University Hospital, 00189 Rome, ItalyRadiology Unit, Department of Medical-Surgical Sciences and Translational Medicine, Sant’Andrea University Hospital, 00189 Rome, ItalyHematology, Department of Translational and Precision Medicine, Sapienza University, 00185 Rome, ItalyHematology, Department of Translational and Precision Medicine, Sapienza University, 00185 Rome, ItalyHematology Unit, Department of Clinical and Molecular Medicine, Sant’Andrea University Hospital, Sapienza University, 00189 Rome, Italy<b>Introduction:</b> Primary bone lymphoma (PBL) is a rare clinical entity, accounting for less than 5% of all extranodal non-Hodgkin lymphomas and approximately 5% of primary bone tumors. Diffuse large B-cell lymphoma (DLBCL) is the most common histotype, accounting for about 80% of all PBL cases. Conversely, the incidence of indolent primary bone lymphomas (iPBL) represents less than 1% of all reported PBL cases, and data on these rarer lymphomas are scarce. Drawing on diagnostic criteria developed by the World Health Organization (WHO) and the International Extranodal Lymphoma Study Group (IELSG), we report a rare case of primary bone follicular lymphoma, focusing specifically on the clinical presentation and treatment. Discussion: Additionally, we provide a systematic review of the literature data on this very rare lymphoproliferative entity.https://www.mdpi.com/2673-6357/5/4/28PBLDLBCLlymphomafollicular lymphoma |
| spellingShingle | Chiara Togni Giacinto La Verde Sabrina Pelliccia Maria Paola Bianchi Arianna Di Napoli Tiziana Lanzolla Marta Zerunian Andrea Laghi Gianluca Maiorana Ambra Taglietti Agostino Tafuri A Rare Case of Primary Bone Follicular Lymphoma with Multiple Osteolytic Lesions: A Case Report and Review of the Literature Hemato PBL DLBCL lymphoma follicular lymphoma |
| title | A Rare Case of Primary Bone Follicular Lymphoma with Multiple Osteolytic Lesions: A Case Report and Review of the Literature |
| title_full | A Rare Case of Primary Bone Follicular Lymphoma with Multiple Osteolytic Lesions: A Case Report and Review of the Literature |
| title_fullStr | A Rare Case of Primary Bone Follicular Lymphoma with Multiple Osteolytic Lesions: A Case Report and Review of the Literature |
| title_full_unstemmed | A Rare Case of Primary Bone Follicular Lymphoma with Multiple Osteolytic Lesions: A Case Report and Review of the Literature |
| title_short | A Rare Case of Primary Bone Follicular Lymphoma with Multiple Osteolytic Lesions: A Case Report and Review of the Literature |
| title_sort | rare case of primary bone follicular lymphoma with multiple osteolytic lesions a case report and review of the literature |
| topic | PBL DLBCL lymphoma follicular lymphoma |
| url | https://www.mdpi.com/2673-6357/5/4/28 |
| work_keys_str_mv | AT chiaratogni ararecaseofprimarybonefollicularlymphomawithmultipleosteolyticlesionsacasereportandreviewoftheliterature AT giacintolaverde ararecaseofprimarybonefollicularlymphomawithmultipleosteolyticlesionsacasereportandreviewoftheliterature AT sabrinapelliccia ararecaseofprimarybonefollicularlymphomawithmultipleosteolyticlesionsacasereportandreviewoftheliterature AT mariapaolabianchi ararecaseofprimarybonefollicularlymphomawithmultipleosteolyticlesionsacasereportandreviewoftheliterature AT ariannadinapoli ararecaseofprimarybonefollicularlymphomawithmultipleosteolyticlesionsacasereportandreviewoftheliterature AT tizianalanzolla ararecaseofprimarybonefollicularlymphomawithmultipleosteolyticlesionsacasereportandreviewoftheliterature AT martazerunian ararecaseofprimarybonefollicularlymphomawithmultipleosteolyticlesionsacasereportandreviewoftheliterature AT andrealaghi ararecaseofprimarybonefollicularlymphomawithmultipleosteolyticlesionsacasereportandreviewoftheliterature AT gianlucamaiorana ararecaseofprimarybonefollicularlymphomawithmultipleosteolyticlesionsacasereportandreviewoftheliterature AT ambrataglietti ararecaseofprimarybonefollicularlymphomawithmultipleosteolyticlesionsacasereportandreviewoftheliterature AT agostinotafuri ararecaseofprimarybonefollicularlymphomawithmultipleosteolyticlesionsacasereportandreviewoftheliterature AT chiaratogni rarecaseofprimarybonefollicularlymphomawithmultipleosteolyticlesionsacasereportandreviewoftheliterature AT giacintolaverde rarecaseofprimarybonefollicularlymphomawithmultipleosteolyticlesionsacasereportandreviewoftheliterature AT sabrinapelliccia rarecaseofprimarybonefollicularlymphomawithmultipleosteolyticlesionsacasereportandreviewoftheliterature AT mariapaolabianchi rarecaseofprimarybonefollicularlymphomawithmultipleosteolyticlesionsacasereportandreviewoftheliterature AT ariannadinapoli rarecaseofprimarybonefollicularlymphomawithmultipleosteolyticlesionsacasereportandreviewoftheliterature AT tizianalanzolla rarecaseofprimarybonefollicularlymphomawithmultipleosteolyticlesionsacasereportandreviewoftheliterature AT martazerunian rarecaseofprimarybonefollicularlymphomawithmultipleosteolyticlesionsacasereportandreviewoftheliterature AT andrealaghi rarecaseofprimarybonefollicularlymphomawithmultipleosteolyticlesionsacasereportandreviewoftheliterature AT gianlucamaiorana rarecaseofprimarybonefollicularlymphomawithmultipleosteolyticlesionsacasereportandreviewoftheliterature AT ambrataglietti rarecaseofprimarybonefollicularlymphomawithmultipleosteolyticlesionsacasereportandreviewoftheliterature AT agostinotafuri rarecaseofprimarybonefollicularlymphomawithmultipleosteolyticlesionsacasereportandreviewoftheliterature |