RUNX1::MECOM rearrangement in myeloid neoplasm post cytotoxic therapy following sarcoma treatment: a case presentation and review of the literature

RUNX1::MECOM rearrangement in myeloid neoplasm post cytotoxic therapy following sarcoma treatment: a case presentation and review of the literature

Objectives Myeloid neoplasms occurring after cytotoxic therapy (MN-pCT), previously termed therapy-related myelodysplastic neoplasia (MDS) or therapy-related acute myelogenous leukemia (AML), pose significant treatment challenges due to high resistance, poor chemotherapy tolerance, and relapse.Metho...

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Main Authors: Miriam Sandnes, Øystein Sefland, Irini Ktoridou-Valen, Rakel Brendsdal Forthun, Hilde Kollsete Gjelberg, Lars Henrik Dahl Hamnvik, Håkon Reikvam, Tor Henrik Andersson Tvedt
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Hematology
Subjects:
acute myeloid leukemia
RUNX1::MECOM
myeloid neoplasms post-cytotoxic therapy
immunphenotype
translocation
fusion transcript
Online Access:https://www.tandfonline.com/doi/10.1080/16078454.2025.2483094
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https://www.tandfonline.com/doi/10.1080/16078454.2025.2483094

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