Identifying ferroptosis-related genes in lung adenocarcinoma using random walk with restart in the PPI network

Identifying ferroptosis-related genes in lung adenocarcinoma using random walk with restart in the PPI network

Abstract Lung adenocarcinoma (LUAD), the most common non-small cell lung cancer subtype, often presents with subtle early symptoms leading to delayed diagnosis. Ferroptosis, a cell death process associated with iron metabolism dysregulation, has been linked to cancer onset, progression, and treatmen...

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Bibliographic Details
Main Authors: Can Liu, Peng He, Ru Qiao, Xiaoyan Yang, Changsong Ding, Fuyuan He
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Lung adenocarcinoma
Ferroptosis
Machine learning
Random walk with restart
PPI network
Tumor microenvironment
Online Access:https://doi.org/10.1038/s41598-025-14307-2
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https://doi.org/10.1038/s41598-025-14307-2

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