Direct Synthesis of 2-(4-Hydroxyphenoxy)benzamide Derivatives from 2-Aryloxybenzamide via PhIO-Mediated Oxidation Reaction

Direct Synthesis of 2-(4-Hydroxyphenoxy)benzamide Derivatives from 2-Aryloxybenzamide via PhIO-Mediated Oxidation Reaction

The 2-(4-hydroxyphenoxy)benzamide scaffold is frequently found in a variety of bioactive compounds, displaying a broad spectrum of properties, such as antibacterial and antitumor effects. In this study, we developed a new method for synthesizing 2-(4-hydroxyphenoxy)benzamide derivatives from 2-arylo...

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Bibliographic Details
Main Authors: Zhenhua Shang, Dechen Jiao, Haoran Cheng, Daowei Huang
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Molecules
Subjects:
2-(4-hydroxyphenoxy)benzamide
2-aryloxybenzamide
PhIO
hypervalent iodine
Online Access:https://www.mdpi.com/1420-3049/29/24/6048
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