Evaluation of polymorphism in BCL-2, PD-1, and PD-L1 genes in myelodysplastic neoplasms

B-cell CLL/lymphoma 2 (BCL-2) family proteins regulate apoptosis, while programmed cell death protein 1 (PD-1) and programmed death-ligand 1 (PD-L1) act as negative regulators of the immune system. An association has been found between abnormalities in BCL-2 and PD-1/PD-L1 proteins and susceptibilit...

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Bibliographic Details
Main Authors: Bartłomiej Kuszczak, Piotr Łacina, Marta Dratwa-Kuźmin, Katarzyna Bogunia-Kubik, Tomasz Wróbel, Justyna Rybka
Format: Article
Language:English
Published: Via Medica 2025-01-01
Series:Acta Haematologica Polonica
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Online Access:https://journals.viamedica.pl/acta_haematologica_polonica/article/view/104373
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