A pilot study on LC–MS/MS quantification of remifentanil, etomidate, and rocuronium in maternal and fetal serum microsamples

A pilot study on LC–MS/MS quantification of remifentanil, etomidate, and rocuronium in maternal and fetal serum microsamples

Abstract While remifentanil, etomidate, and rocuronium are increasingly used for cesarean section due to their favorable hemodynamic stability and fetal safety profile, their pharmacokinetics and potential effects on neonates remain poorly understood. This study developed and validated a rapid, sens...

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Bibliographic Details
Main Authors: Hao Liu, Meng Cai, Yong Peng, Jing-kun Miao, Jin Yu
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Anesthetics
Caesarean section
LC–MS/MS
Newborn
Online Access:https://doi.org/10.1038/s41598-025-09454-5
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https://doi.org/10.1038/s41598-025-09454-5

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