Improvement of L-Tryptophan Production in <i>Escherichia coli</i> Using Biosensor-Based, High-Throughput Screening and Metabolic Engineering

Improvement of L-Tryptophan Production in <i>Escherichia coli</i> Using Biosensor-Based, High-Throughput Screening and Metabolic Engineering

The demand for L-tryptophan (L-Trp) has been rapidly increasing across various industries, including pharmaceuticals, food, and animal feed. However, traditional production methods have been unable to efficiently meet this growing demand. Hence, this study aimed to develop strategies for enhancing L...

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Bibliographic Details
Main Authors: Zhenghao Gao, Fengli Wu, Zhidan Zhang, Xu Zhang, Yuansen Hu, Qinhong Wang, Shuaibing Zhang
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Fermentation
Subjects:
<i>Escherichia coli</i>
L-Tryptophan
biosensor
high-throughput screening
metabolic engineering
ARTP mutagenesis
Online Access:https://www.mdpi.com/2311-5637/11/5/267
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