Nitric oxide releasing nanofiber stimulates revascularization in response to ischemia via cGMP-dependent protein kinase.

Nitric oxide releasing nanofiber stimulates revascularization in response to ischemia via cGMP-dependent protein kinase.

Nitric oxide (NO) promotes angiogenesis via various mechanisms; however, the effective transmission of NO in ischemic diseases is unclear. Herein, we tested whether NO-releasing nanofibers modulate therapeutic angiogenesis in an animal hindlimb ischemia model. Male wild-type C57BL/6 mice with surgic...

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Main Authors: Kyung Hye Lee, Min-Young Song, Sora Lee, JinSun Park, Jung Hee Kang, Haneul Cho, Ki-Bum Kim, Soo Ji Son, Xian Wu Cheng, Young Ju Lee, Gi-Ja Lee, Jae Ho Shin, Weon Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0303758&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0303758&type=printable

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