Screening and validation of key genes involved in castration-resistant prostate cancer based on transcriptomics sequencing

Screening and validation of key genes involved in castration-resistant prostate cancer based on transcriptomics sequencing

Abstract Prostate cancer is one of the most common malignant tumors occurring in the male reproductive system. Androgen deprivation therapy (ADT) is the primary treatment for prostate cancer. However, approximately 10–20% of advanced prostate cancer patients progress to castration-resistant prostate...

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Bibliographic Details
Main Authors: Guangquan Tong, Xiaomeng Jing, Yuning Yang, Xiaowei Wang, Junlin Lu, Jingyi Hu, Yang Wang, Farra Aidah Jumuddin, Wenjing Zhang, Yuesheng Lv
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Castration-resistant
Prostate cancer
Transcriptomics
Biomarkers
Online Access:https://doi.org/10.1038/s41598-025-11397-w
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https://doi.org/10.1038/s41598-025-11397-w

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