Class II HLA diabetogenic markers in an Udmurtian population: genotype dependence, the role of DQ trans-heterodimers

Class II HLA diabetogenic markers in an Udmurtian population: genotype dependence, the role of DQ trans-heterodimers

Aim. To analyse association of class II HLA genotype (DRB1, DQA1, DQB1) with type 1 diabetes mellitus (DM1) in an Udmurtian population. Materials and methods. The case-control method was applied in the study involving 29 children with DM1 and 97 age-matched healthy subjects. HLAalleles were identi...

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Main Authors: Olga Nikolavna Ivanova, Sergey Alexandrovich Prokof'ev, Yana Stanislavovna Zvereva, Tatiana Viktorovna Kovalenko, Andrey Vladimirovich Blinov, Valentina Alexandrovna Peterkova
Format: Article
Language:English
Published: Endocrinology Research Centre 2009-09-01
Series:Сахарный диабет
Subjects:
dqa1
type 1 diabetes mellitus
class ii hla drb1
dqb1 genes
role of dq heterodimers
udmurtian population
Online Access:https://www.dia-endojournals.ru/jour/article/view/5449
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