Evaluation of informativeness of DNA methylation degree of DKK4 gene as a diagnostic criterion in breast adenocarcinoma

Evaluation of informativeness of DNA methylation degree of DKK4 gene as a diagnostic criterion in breast adenocarcinoma

Abnormalities of DNA methylation play a significant role in initiation and progression of tumors. The aim of the study was the evaluation of the quantitative determination of hypermethylation of DKK4 gene first exon as a biomarker of the breast epithelial cells malignant transformation in patients w...

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Bibliographic Details
Main Authors: Zaporozhan V.N., Bubnov V.V., Marichereda V.G., Petrovsky Yu.Yu., Andronov D.Yu.
Format: Article
Language:English
Published: Dnipro State Medical University 2014-09-01
Series:Medičnì Perspektivi
Subjects:
DNA methylation
DKK4 gene
CG site
breast adenocarcinoma
Online Access:http://medpers.dsma.dp.ua/issues/2014/N3/18-23.pdf
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http://medpers.dsma.dp.ua/issues/2014/N3/18-23.pdf

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