The AP-1 factor JUNB correlates with poor survival of patients with esophageal adenocarcinoma

The AP-1 factor JUNB correlates with poor survival of patients with esophageal adenocarcinoma

Abstract Malignant cells have in contrast to non-transformed cells de-regulated transcriptional networks. The activator protein-1 (AP-1) transcription factor complex is expressed in many cancer entities including adenocarcinomas and has been correlated to de-regulated transcription and tumor-promoti...

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Main Authors: Nikolai Schleussner, Karl Knipper, Ella Leugner, Christian Goddemeier, Uraz Yasar, Naita M. Wirsik, Jin-On Jung, Hans F. Fuchs, Lars M. Schiffmann, Alexander Quaas, Christiane J. Bruns, Thomas Schmidt
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Esophageal adenocarcinoma
AP-1
CJUN
JUNB
Targeted therapy
Individualized medicine
Online Access:https://doi.org/10.1038/s41598-025-07393-9
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https://doi.org/10.1038/s41598-025-07393-9

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