Investigating Macular Tissue Integrity Index as a Novel Biomarker in Geographic Atrophy

Investigating Macular Tissue Integrity Index as a Novel Biomarker in Geographic Atrophy

Purpose: The rate of geographic atrophy (GA) enlargement is commonly used as an outcome in clinical trials. However, this metric typically lacks specificity for central macular involvement and structure–function relationships. We propose a targeted approach in monitoring GA progression within the ce...

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Main Authors: Bethany M. Erb, MD, Elaine Botros, Thomas F. Saunders, OD, Anna-Maria Haas, MD, Rick Voland, PhD, Rachel Linderman, PhD, Amitha Domalpally, MD, PhD, Karl G. Csaky, MD
Format: Article
Language:English
Published: Elsevier 2025-11-01
Series:Ophthalmology Science
Subjects:
Age-related macular degeneration
Autofluorescence
Ellipsoid zone
Geographic atrophy
Online Access:http://www.sciencedirect.com/science/article/pii/S2666914525001691
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