Increased Susceptibility of <i>Rousettus aegyptiacus</i> Bats to Respiratory SARS-CoV-2 Challenge Despite Its Distinct Tropism for Gut Epithelia in Bats

Increased Susceptibility of <i>Rousettus aegyptiacus</i> Bats to Respiratory SARS-CoV-2 Challenge Despite Its Distinct Tropism for Gut Epithelia in Bats

Increasing evidence suggests bats are the ancestral hosts of the majority of coronaviruses. In general, coronaviruses primarily target the gastrointestinal system, while some strains, especially Betacoronaviruses with the most relevant representatives SARS-CoV, MERS-CoV, and SARS-CoV-2, also cause s...

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Bibliographic Details
Main Authors: Björn-Patrick Mohl, Claudia Blaurock, Angele Breithaupt, Alexander Riek, John R. Speakman, Catherine Hambly, Marcel Bokelmann, Gang Pei, Balal Sadeghi, Anca Dorhoi, Anne Balkema-Buschmann
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Viruses
Subjects:
SARS-CoV-2
<i>Rousettus aegyptiacus</i>
tissue tropism
respiratory tract
digestive tract
viral infection
Online Access:https://www.mdpi.com/1999-4915/16/11/1717
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https://www.mdpi.com/1999-4915/16/11/1717

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