REVERSE model: a novel approach in medical research

Abstract Background Randomized controlled trials are considered the gold standard but they are limited by high costs and external validity. The REVERSE model is introduced to address these challenges. Methods The REVERSE model encompasses two sequential phases. First, in the data mining phase, compa...

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Bibliographic Details
Main Authors: Luca Saba, Gianluca De Rubeis, Francesco Pisu
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Trials
Online Access:https://doi.org/10.1186/s13063-025-08974-9
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