Taurine alleviated paraquat-induced oxidative stress and gut-liver axis damage in weaned piglets by regulating the Nrf2/Keap1 and TLR4/NF-κB signaling pathways

Taurine alleviated paraquat-induced oxidative stress and gut-liver axis damage in weaned piglets by regulating the Nrf2/Keap1 and TLR4/NF-κB signaling pathways

Abstract Background Oxidative stress can impair intestinal barrier function and cause liver damage, resulting in reduced animal productivity. Paraquat (PQ) induces significant oxidative stress in weaned piglets. The antioxidant, anti-inflammatory, and metabolic regulatory functions of taurine (Tau),...

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Bibliographic Details
Main Authors: Chen Chen, Min Qi, Weilong Zhang, Fanxing Chen, Zhihong Sun, Weizhong Sun, Wenjie Tang, Zhenguo Yang, Xuan Zhao, Zhiru Tang
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Journal of Animal Science and Biotechnology
Subjects:
Antioxidant
Gut-liver axis
Immune response
Intestinal barrier
Lipopolysaccharide
Paraquat
Online Access:https://doi.org/10.1186/s40104-025-01244-3
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https://doi.org/10.1186/s40104-025-01244-3

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