Comparison of the efficacy of curcumin and its nano formulation on dexamethasone-induced hepatic steatosis, dyslipidemia, and hyperglycemia in Wistar rats

Comparison of the efficacy of curcumin and its nano formulation on dexamethasone-induced hepatic steatosis, dyslipidemia, and hyperglycemia in Wistar rats

Background and objective: Insulin resistance is a primary feature of type 2 diabetes. This study compared the effects of curcumin and its nanoformulation on insulin resistance, fasting blood sugar, liver function, GLUT4, lipid profile, and oxidative stress in the liver and pancreas in a diabetic mod...

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Main Authors: Amany M. Hamed, Dalia A. Elbahy, Ahmed RH. Ahmed, Shymaa A. Thabet, Rasha Abdeen Refaei, Islam Ragab, Safaa Mohammed Elmahdy, Ahmed S. Osman, Azza MA. Abouelella
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Heliyon
Subjects:
Type 2 diabetes
Nano-curcumin
Liver steatosis
Insulin resistance
Antihyperglycemic
Antihyperlipidemic
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024170740
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