FKBP prolyl isomerase 4: a potential target for heart failure and cardioprotective effects via leonurine-pretreated mesenchymal stem cell-derived exosomes

Abstract Background The use of mesenchymal stem cell-derived exosomes (MSC-EXOs) is a promising strategy for treating heart failure. Pretreatment of MSCs with cardioprotective agents, such as leonurine, has the potential to augment the therapeutic efficacy of their EXO activities. However, the cardi...

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Bibliographic Details
Main Authors: Zhaoyi Li, De-Chong Zheng, Ruixiang Wang, Qian Ding, Yi Zhun Zhu
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Stem Cell Research & Therapy
Online Access:https://doi.org/10.1186/s13287-025-04497-x
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