Astragaloside IV alleviates inflammation and improves myocardial metabolism in heart failure mice with preserved ejection fraction

Astragaloside IV alleviates inflammation and improves myocardial metabolism in heart failure mice with preserved ejection fraction

BackgroundHeart failure with preserved ejection fraction (HFpEF) has grown to become the dominant form of heart failure worldwide. However, no unequivocally effective treatment for HFpEF has been identified in clinical trials. In this study, we report that Astragaloside IV (AS-IV) can be used to tre...

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Bibliographic Details
Main Authors: Xiao Wang, Xinting Chen, Yuting Wang, Xinyu He, Lan Li, Xiaodan Wang, Yuting Huang, Guanwei Fan, Jingyu Ni
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Pharmacology
Subjects:
HFpEF
astragaloside IV
inflammation
metabolism
mitochondria
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1467132/full
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